Cell death in diabetes
نویسندگان
چکیده
منابع مشابه
Epidemiology and Death Trends Due to Diabetes in Iran
Aims: Diabetes mortality undergoes a growing trend worldwide that results in reducing life expectancy in society. Diabetes has been a significant health challenge in recent decades and imposed a lot of economic burden on the community. The present study aimed to evaluate the trend of diabetes mortality in Iran over five years. Methods & Materials: The mortality data published by the Ministry o...
متن کاملb-Cell death during progression to diabetes
792 NATURE | VOL 414 | 13 DECEMBER 2001 | www.nature.com Type 1 diabetes is an autoimmune disease resulting from specific destruction of the insulin-producing b-cells of the islets of Langerhans of the pancreas. It has two distinct phases: insulitis, when a mixed population of leukocytes invades the islets; and diabetes, when most b-cells have been killed off, and there is no longer sufficient ...
متن کاملMetabolomics and Cell Therapy in Diabetes Mellitus
Diabetes with a broad spectrum of complications has become a global epidemic metabolic disorder. Till now, several pharmaceutical and non-pharmaceutical therapeutic approaches were applied for its treatment. Cell-based therapies have become promising methods for diabetes treatment. Better understanding of diabetes pathogenesis and identification of its specific biomarkers along with evaluation ...
متن کاملRole of Apoptosis in Pancreatic -Cell Death in Diabetes
Apoptosis is a physiological form of cell death that occurs during normal development, and critical mediators of this process include caspases, reactive oxygen species, and Ca. Excessive apoptosis of the pancreatic -cell has been associated with diabetes. Consequently, apoptosis research has focused on how infiltrating macrophages or cytotoxic T-cells might kill pancreatic -cells using cytokine...
متن کاملDifferent cell death types determination in juvenile mice ovarian follicles
Follicular atresia is a phenomenon that leads to evacuation of the ovary from the oocytes and the occurrence of menopause. The contribution of various types of cell death in atresia at different follicular developmental stages requires extensive investigation. In this study, we evaluated 3 types of programmed </...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2003
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri1048